Yes

Argent for VMware leverages off VMware PowerCLI to automate all aspects of VMware monitoring

VMware PowerCLI 5.0 supports all versions of VMware, including vCenter Server 5.0 and VMware ESXi 5.0

Simply ensure you have the latest version of VMware PowerCLI 5.0 installed on the Argent for VMware Main Engine and Trusted Agents